| Inter | 0-1 | Parma | Giuseppe Meazza | 15 Set | h.15:00 |
| Napoli | 1-0 | Fiorentina | Diego Armando Maradona | 15 Set | h.18:00 |
| Frosinone | 0-5 | Sampdoria | Benito Stirpe | 15 Set | h.20:30 |
| Roma | 2-2 | ChievoVerona | Olimpico | 16 Set | h.12:30 |
| Genoa | 1-0 | Bologna | Luigi Ferraris | 16 Set | h.15:00 |
| Juventus | 2-1 | Sassuolo | Allianz Stadium | 16 Set | h.15:00 |
| Udinese | 1-1 | Torino | Bluenergy Stadium - Stadio Friuli | 16 Set | h.15:00 |
| Empoli | 0-1 | Lazio | Carlo Castellani - Computer Gross Arena | 16 Set | h.18:00 |
| Cagliari | 1-1 | Milan | Unipol Domus | 16 Set | h.20:30 |
| SPAL | 2-0 | Atalanta | Paolo Mazza | 17 Set | h.20:30 |