| Juventus | 1-0 | Lecce | Allianz Stadium | 26 Set | h.20:45 |
| Cagliari | 1-3 | Milan | Unipol Domus | 27 Set | h.18:30 |
| Empoli | 1-0 | Salernitana | Carlo Castellani - Computer Gross Arena | 27 Set | h.18:30 |
| Verona | 0-1 | Atalanta | Marcantonio Bentegodi | 27 Set | h.18:30 |
| Inter | 1-2 | Sassuolo | Giuseppe Meazza | 27 Set | h.20:45 |
| Lazio | 2-0 | Torino | Olimpico | 27 Set | h.20:45 |
| Napoli | 4-1 | Udinese | Diego Armando Maradona | 27 Set | h.20:45 |
| Frosinone | 1-1 | Fiorentina | Benito Stirpe | 28 Set | h.18:30 |
| Monza | 0-0 | Bologna | U-Power Stadium | 28 Set | h.18:30 |
| Genoa | 4-1 | Roma | Luigi Ferraris | 28 Set | h.20:45 |