| Galatasaray | 1-0 | Liverpool | Rams Park | 10 Mar | h. 18:45 |
| Atalanta | 1-6 |  Bayern Monaco | New Balance Arena | 10 Mar | h. 21:00 |
| Atletico Madrid | 5-2 |  Tottenham Hotspur | Riyadh Air Metropolitano | 10 Mar | h. 21:00 |
| Newcastle United | 1-1 |  Barcellona | St James Park | 10 Mar | h. 21:00 |
| Bayer Leverkusen | 1-1 |  Arsenal | BayArena | 11 Mar | h. 18:45 |
| Bodo/Glimt | 3-0 | Sporting Lisbona | Aspmyra Stadion | 11 Mar | h. 21:00 |
| PSG | 5-2 |  Chelsea | Parco dei Principi | 11 Mar | h. 21:00 |
Real Madrid  | 3-0 | Manchester City | Santiago Bernabeu | 11 Mar | h. 21:00 |