| Barcellona | 3-1 | Benfica | Estadi Olímpic Lluis Companys | 11 Mar | h. 18:45 |
| Bayer Leverkusen | 0-2 | Bayern Monaco | BayArena | 11 Mar | h. 21:00 |
| Inter | 2-1 | Feyenoord | Giuseppe Meazza | 11 Mar | h. 21:00 |
Liverpool  | 1-5 (d.c.r) |  Paris Saint Germain | Anfield Road | 11 Mar | h. 21:00 |
Lilla  | 1-2 |  Borussia Dortmund | Stade Pierre-Mauroy | 12 Mar | h. 18:45 |
| Arsenal | 2-2 |  PSV Eindhoven | Emirates Stadium | 12 Mar | h. 21:00 |
Aston Villa  | 3-0 | Club Bruges | Villa Park | 12 Mar | h. 21:00 |
| Atletico Madrid | 3-4 (d.c.r) | Real Madrid | Riyadh Air Metropolitano | 12 Mar | h. 21:00 |