| Kairat Almaty | 0-1 |  Levski Sofia | Turkistan Arena | 11 Ago | h. 17:00 |
| Bodo/Glimt | 3-2 (d.t.s) |  Royale Union Saint-Gilloise | Aspmyra Stadion | 11 Ago | h. 18:00 |
| Sabah Baku | 4-0 |  AGF Aarhus | Bank Respublika Arena | 11 Ago | h. 18:00 |
Kauno Zalgiris  | 1-2 | Dinamo Zagabria | Darius and Girėnas Stadium | 11 Ago | h. 19:00 |
| NEC Nijmegen | 2-1 (d.t.s) | Olympiakos | Goffertstadion | 11 Ago | h. 19:30 |
Stella Rossa  | 0-2 | Hapoel Beer Sheva | Red Star Stadium | 11 Ago | h. 20:00 |
Celje  | 2-0 |  Ararat-Armenia | Stadio Z'dežele | 11 Ago | h. 20:15 |
Slovan Bratislava  | 2-0 | Mjällby | Tehelné pole | 11 Ago | h. 20:15 |
| Sturm Graz | 0-1 | Fenerbahce | Liebenauer Stadium | 11 Ago | h. 20:30 |
Olympique Lione  | 3-0 |  Sparta Praga | Parc Olympique Lyonnais | 11 Ago | h. 21:00 |