| Twente | 2-0 | Zwolle | De Grolsch Veste | 17 Apr | h.18:30 | |
| Heerenven | 2-0 | Den Haag | Abe Lenstra Stadion | 17 Apr | h.20:45 | |
| Az Alkmaar | 4-3 | Vitesse | AFAS Stadion | 18 Apr | h.18:30 | |
| Roda | 2-2 | PSV Eindhoven | Parkstad Limburg Stadion | 18 Apr | h.18:30 | |
| Excelsior | 2-2 | Heracles | Stadion Woudestein | 18 Apr | h.19:45 | |
| Ajax | 4-1 | Venlo | Amsterdam ArenA | 18 Apr | h.20:45 | |
| Sparta Rotterdam | 2-1 | Breda | Het Kasteel | 18 Apr | h.20:45 | |
| Utrecht | 1-1 | Groningen | Stadion Galgenwaard | 19 Apr | h.18:30 | |
| Willem II | 1-5 | Feyenoord | Willem II Stadium | 19 Apr | h.20:45 |
