| West Ham | 2-3 | Tottenham | The Stadium | 23 Set | h.13:30 |
| Burnley | 0-0 | Huddersfield Town | Turf Moor | 23 Set | h.16:00 |
| Everton | 2-1 | Bournemouth | Goodison Park | 23 Set | h.16:00 |
| Manchester City | 5-0 | Crystal Palace | City of Manchester Stadium | 23 Set | h.16:00 |
| Southampton | 0-1 | Manchester United | St Mary's Stadium | 23 Set | h.16:00 |
| Stoke City | 0-4 | Chelsea | Bet365 Stadium | 23 Set | h.16:00 |
| Swansea City | 1-2 | Watford | Liberty Stadium | 23 Set | h.16:00 |
| Leicester | 2-3 | Liverpool | King Power Stadium | 23 Set | h.18:30 |
| Brighton | 1-0 | Newcastle | The Amex Stadium | 24 Set | h.17:00 |
| Arsenal | 2-0 | West Bromwich | Emirates Stadium | 25 Set | h.21:00 |
